pentobarbital will decrease the level or result of hydrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will decrease the level or result of repaglinide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or impact of sulfamethoxazole by impacting hepatic enzyme CYP2C9/10 metabolism. Small/Significance Unfamiliar.
Elderly or debilitated individuals may react to barbiturates with marked melancholy, exhilaration, and confusion; in some individuals, barbiturates repeatedly generate enjoyment in lieu of depression
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pentobarbital will minimize the level or outcome of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or result of ondansetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. No dosage adjustment for ondansetron is suggested for individuals on these medication.
Barbiturates can induce hepatic microsomal enzymes leading to increased metabolism and diminished anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); clients stabilized on anticoagulant therapy may call for dosage changes if barbiturates are included to or withdrawn from their dosage program
pentobarbital will lower the level or result of estradiol vaginal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will reduce the level or outcome of ramelteon by influencing hepatic enzyme CYP2C9/10 metabolism. Small/Significance Mysterious.
Keep track of Intently (1)pentobarbital will lessen the extent or effect of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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pentobarbital will lower the level or influence of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Check Intently (one)pentobarbital will reduce the extent or impact of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.